Activella is used for the treatment of mild to serious symptoms of menopause (like hot flashes, itching, dryness or burning sensation in or around the vagina).

It also helps in preventing osteoporosis (weakening of bones) in females after menopause. Activella is a combination of progestin hormones and estrogen. It helps in replacing natural estrogen and progestin in women who are unable to produce enough of these hormones after menopause and can be purchased only with a doctor's prescription.